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KMID : 1123920090230061399
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Korean Journal of Oriental Physiology and Pathology
2009 Volume.23 No. 6 p.1399 ~ p.1403
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Effect of Swimming Exercise Training and Gastrodia Elata Blume Extract Administration on Oxidative Enzyme Activity in Streptozotocin-induced Diabetic Rat
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Kim Eun-Jung
Kim Young-Eok
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Abstract
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The aim of the present study was to evaluate the possibility of protective effectness of swimming exercise and Gastrodia elata blume oral administration against beta-cell damage in streptozotocin (STZ)-induced diabetes in rats. The animals were divided into five groups: the normal group(n=10), the STZ-induced diabetes group(n=10), the STZ-induced diabetes and moderate-intensity exercise group(n=10), the STZ-induced diabetes Gastrodia elata blume(300 ㎎/㎏) oral administration group(n=10), the STZ-induced diabetes and moderate-intensity exercise and Gastrodia elata blume(300 ㎎/㎏) oral administration group(n=10). Animals in the exercise groups were made to swim moderate swimming exercise protocols once a day for 4 consecutive weeks. Serum glucose concentration and insulin level, superoxide dismutase (SOD) and catalase (CAT) were measured in serum. Swimming exercise and Gastrodia elata blume extract administrationhas shown anti-diabetic effect probably through decreasing serum glucose and insulin level and increasing antioxidant enzyme activity.
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KEYWORD
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diabetes, Gastrodia elata blume, oxidative stress, swimming exercise
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